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KMID : 0357820100340020147
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Korean Journal of Legal Medicine
2010 Volume.34 No. 2 p.147 ~ p.151
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Null and Duplicated Alleles of 17 Y-STR Haplotypes in Koreans and Considerations for Forensic Application
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Cho Nam-Soo
Yoo Seoong-Yeon
Hwang Jung-Ho
Seong Ki-Min
Chung Nak-Eun
Lee Won-Tae
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Abstract
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The analysis of Y chromosome polymorphisms has become common place for the identification of male component in forensic cases. In male/female mixtures of many rape cases, Y-STRs are also very useful for the determination of contributors’ number. During the analyses of 17 Y-STR haplotypes for forensic applications using the AmpFlSTR® YfilerTM system, a number of null and duplicated alleles (40 out of 2144 subjects) were discovered. Interestingly, two haplotypes should focus the attention on forensic interpretation of Y-STR haplotype profiles, because multiple mutational events at various loci can be interpreted as a wrong mixed or allele drop-out profile.
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KEYWORD
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Y chromosome STR, AmpFlSTR® YfilerTM system, null allele, duplicated allele, database
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